/* Popup de referencias*/
.reference_popup {
    border-radius: 5pt;
    font-size: 8.9pt;
    background-color: white;
    border-color: rgba(0, 0, 0, 0);
    box-shadow: 0 0 5px rgba(0, 0, 0, 0.9);
    border-style: solid;
    border-width: 1px;
    position: absolute;
    padding: 10px;
    z-index: 1;
    line-height: 1.5;
    overflow: visible !important;
    max-width: calc(89% - 20px);
    font-style: normal !important;

}

.start_hidden {
    display: none;
}

.accordion-header-1 {
    box-sizing: border-box;
    width: 100%;
}

.accordion-header-1:hover {
    background-color: #e0e0e0;
    border-radius: 5px;

}

.accordion-body {
    position: relative;
    background: #F7F7F7;
    /* overflow: inherit !important; */
    overflow: visible !important;

}

@media (max-width: 768px) {

    .emd-drugs-full-descriptions table,
    .accordion-body table {
        border: 0;
        overflow-x: auto;
        display: block;
    }
}

.accordion-button:not(.collapsed) {
    color: #000;
    background-color: rgba(0, 0, 0, 0);
}

.icon-menu:before {
    content: "\e911";
    color: #fff !important;
}

.emd-main-menu ul li span:before {
    font-size: 1.25rem;
    color: inherit;
}


#btn-lupe::before {
    content: "\e90f";
    color: #fff;
}


#btn-lupe.active::before {
    color: #4F4D4D;
}


.emd-drugs-full-descriptions .accordion-header {
    border-bottom: hidden;
}

.accordion-flush>.accordion-item>.accordion-collapse {

    margin-top: 0rem;
}

.emd-drugs-full-descriptions p:last-child {
    margin: .4rem 0;
    font-size: .875rem;
}

.emd-drugs-full-descriptions .accordion-body li {
    font-family: "open_sansregular" !important;
    font-size: 0.875rem !important;

}

.emd-drugs-full-descriptions .emd-drugs-accordion__content .accordion-body sup a {
    color: #33f;
    text-decoration: none;
    -webkit-transition: all .3sease;
    transition: all .3sease;
    font-size: 11.5px;
}

.emd-drugs-accordion button {
    padding: .75rem !important;
}



.emd-drugs-title-2 {
    display: grid;
    grid-template-columns: 1fr auto;
    column-gap: .625rem;
}

.reference_number {
    display: inline-block;
    vertical-align: top;
    color: black;
    font-style: normal !important;
}

.reference_text {
    display: inline-block;
    max-width: calc(100% - 20px);
    line-height: 1.2rem;
    overflow-wrap: break-word;
    word-break: break-word;
    color: black;
}

.reference_popup .reference_text a {
    font-size: 11.5px !important;
    word-break: break-word;
    color: #33f !important;
    -webkit-transition: all .3sease;
    transition: all .3sease;
    text-decoration-color: #33f !important;
    font-style: normal !important;

}


.main-search-forms button span {
    font-size: 1rem;
    color: #fff;
}

.accordion-collapse.emd-drugs-accordion__content.collapse.show {
    margin-bottom: 0rem;
}



/* Search bar */
.list-group-item {
    cursor: pointer;
}

.list-group-item a {
    color: rgb(65, 65, 65);
    text-decoration: none;
    display: block;
    width: 100%;
    height: 100%;
}

.list-group-item:hover {

    background-color: #cccccc;
}


.highlighted {
    background-color: #cccccc;
}

.emd-main-menucontent__nav {
    z-index: 9999 !important;
}

#search-results {
    position: absolute;
    z-index: 999;
    width: calc(100% - 10px);
    max-width: calc(100% - 69px);
    left: 11px;
    background-color: white;
    border-top-left-radius: 0;
    border-top-right-radius: 0;
    list-style: none;
    padding: 0;

}

#hidden-search-results {
    position: absolute !important;
    z-index: 999 !important;
    width: 100% !important;
    max-width: 100% !important;
    left: 0 !important;
    top: 100% !important;
    background-color: white !important;
    border-top-left-radius: 0 !important;
    border-top-right-radius: 0 !important;
    list-style: none !important;
    padding: 0 !important;
    box-shadow: 0 0 5px rgba(0, 0, 0, 0.1);
}

.main-search-bar {
    position: relative;
}

.main-search-forms {
    width: 100%;
}

@media (max-width: 768px) {
    #hidden-search-results {
        width: 100% !important;
        left: 0 !important;
    }
}

/* captcha */
.captcha-container {
    display: flex;
    justify-content: center;
    align-items: center;
    width: 100%;
    height: 100%;

    text-align: center;

}

/* Switch Notes*/

.custom-hide-notes .hide-notes-input:checked {
    background-color: green !important;
    border-color: green !important;
}


.btn-secondary-c {
    color: #ffffff !important;
    /* border: 1px solid #e91a1e; */
    border-radius: 5px;
    background-color: #1d315f;
    padding: .25rem 1.25rem;
    font-size: 1rem !important;
    display: block;
    width: 200px;
    text-align: center;
    text-decoration: none !important;
    -webkit-transition: all .3s ease;
    transition: all .3s ease;
}

.btn-secondary-c:hover {
    background-color: #c91e1e;
}

.accordion {
    --bs-accordion-border-width: 0;
}

.btn-secondary-d {
    color: #ffffff !important;
    /* border: 1px solid #e91a1e; */
    border-radius: 20px;
    background-color: #4f4d4d;
    padding: .25rem 1.25rem;
    font-size: 0.85rem !important;
    display: block;
    width: 170px;
    text-align: center;
    text-decoration: none !important;
    -webkit-transition: all .3s ease;
    transition: all .3s ease;
    margin-top: 25px;
}

.btn-secondary-d:hover {
    background-color: #ec0b0b;
}

.btn-secondary-g {
    color: #ffffff !important;
    /* border: 1px solid #e91a1e; */
    border-radius: 20px;
    background-color: #4f4d4d;
    padding: .25rem 1.25rem;
    font-size: 0.85rem !important;
    display: block;
    width: 170px;
    text-align: center;
    text-decoration: none !important;
    -webkit-transition: all .3s ease;
    transition: all .3s ease;
}

.btn-secondary-g:hover {
    background-color: #ec0b0b;
}

.emd-drugs-accordion h2 {
    border-bottom: 0px !important;
    font-family: 'open_sanssemibold' !important;
    /* padding-right: 0.5rem; */
}

.emd-drugs-accordion button {
    font-family: 'open_sanssemibold' !important;
    font-size: 1.125rem;
    line-height: 1.75rem;
    padding: .75rem;
    border-radius: 4px 4px 0 0;
}

/* Index Title */
.emd-p-update p {
    color: #fff;
    font-family: "latobold_italic";
    font-size: 1.2rem;
}

.emd-p-update ul li {
    list-style: none;
    color: #d0d0d0;
    font-family: "open_sansregular" !important;
    font-size: 0.85rem;
    justify-content: center;
    align-items: center;
    width: 100%;
    height: 100%;

    text-align: center;
}

.emd-p-update ul {
    text-align: -webkit-center;
    margin: 0 auto;
    font-family: "open_sansregular" !important;
    font-size: 0.85rem !important;

}

.py-2 {
    padding-top: 1.4rem !important;
    padding-bottom: 1.25rem !important;
}

.emd-p-update2 p {
    margin: 0 auto;
    font-family: "open_sansregular" !important;
    font-size: 0.85rem !important;
    color: #d0d0d0 !important;
}

.emd-p-update ul li a {
    color: #9AA0CE;
    font-family: inherit;
    text-decoration: underline;
}

b,
strong {
    font-weight: bolder;

}

li,
ul {
    line-height: 1.4rem !important;
    font-size: 14.5px !important;
    color: #000000 !important;
}

li {
    font-family: "open_sansregular", "latoregular", Arial, sans-serif;
}

h2 {
    font-size: 19px !important;
    font-family: "open_sanssemibold" !important;
    color: #000000 !important;
}

h3 {
    font-family: "open_sanssemibold" !important;
    font-size: 18px !important;
    color: #000000 !important;

}

h4 {
    font-family: 'open_sansbold' !important;
    font-size: 16.5px !important;
    color: #000000 !important;

}

h5 {
    /* font-size: 1.25rem; */
    font-family: 'open_sanssemibold' !important;
    font-size: 15.5px !important;
    color: #000000 !important;
}

h6 {
    /* font-size: 1.25rem; */
    font-family: 'open_sanssemibold' !important;
    font-size: 15px !important;
}

.notepad {
    background: #E3F7FF;
    padding: 1.25rem;
    position: relative;
    border-radius: 6px
}

p {

    margin: .4rem 0;

}

/* clase para latest updates */
.emd-drugs-terms {
    color: #212529;
    font-family: 'open_sanslight';
    line-height: 1.4rem !important;
    font-size: 14.5px !important;
}


.emd-drugs-accordion .emd-drugs-accordion__content p {
    /* font-family: 'latoregular'; */
    font-family: 'open_sansregular';
    line-height: 1.4rem !important;
    font-size: 14.5px !important;
    color: #000000 !important;
}

.emd-drugs-accordion .emd-drugs-accordion__content li {
    font-family: 'open_sansregular';
    line-height: 1.4rem !important;
    font-size: 14.5px !important;
}

.font_open_sanslight {
    font: 'open_sanslight' !important;
}


.emd-label,
.emd-label-open-access {
    font-family: 'open_sansregular' !important;
    border-radius: 4px !important;
    white-space: nowrap;
    font-size: 10px !important;
    /* min-width: 60px !important; */
    text-align: center !important;
    padding: 4px 6px !important;
    line-height: 1.5 !important;
    margin: 0 0.5rem !important;
    display: inline-block !important;
}

.drug-title {
    display: flex;
    align-items: center;
}

.emd-label-open-access {
    background: #E0E0E0 !important;
    color: #9A9A9A !important;
}

.btn-secondary-e {
    max-width: 300px;
    background: #1d315f;
    color: white;
    border: none;
    text-align: center;
    text-decoration: none !important;
    -webkit-transition: all .3s ease;
    transition: all .3s ease;
}

.btn-secondary-e:hover {
    background-color: #344e8b;
}

.btn-secondary-e:active,
.btn-secondary-e:focus {
    background-color: #344e8b !important;
}

.btn-secondary-q {
    max-width: 300px;
    background: #4f4d4d;
    color: white;
    border: none;
    text-align: center;
    text-decoration: none !important;
    -webkit-transition: all .3s ease;
    transition: all .3s ease;
}

.btn-secondary-q:hover {
    background-color: #212529;
}

.btn-secondary-q:active,
.btn-secondary-:focus {
    background-color: #212529 !important;
}

.btn-info {
    border: none !important;
    -webkit-transition: all .3s ease !important;
    transition: all .3s ease !important;
}


/*  Search Bar*/
.main-search-forms input {
    padding: 0rem 1rem;

}

.main-search-forms input,
.main-search-forms button {
    opacity: 0;
    transform: translateY(-10px);
    animation: fadeIn 0.3s ease-out forwards;
}



@keyframes fadeIn {
    0% {
        opacity: 0;
        transform: translateY(-10px);
    }

    100% {
        opacity: 1;
        transform: translateY(0);
    }
}

@media (max-width: 768px) {

    .emd-drugs-accordion h2,
    .accordion-item.emd-drugs-accordion h2,
    .accordion-item.emd-drugs-accordion .h2 {
        margin-right: 10px;
    }

    .accordion-arrow {
        margin-left: 10px !important;
    }

}





/* favoritos, star, estrella */
.icon-favourite-off:before {
    content: "\e906";
    transition: all 0.1s ease;
}

.icon-favourite-on:hover {
    transition: all 0.1s ease;
    text-shadow: 0 0 10px #dda500, 0 0 40px #dda500, 0 0 60px #dda500;

}

.icon-favourite-off:active:before,
.icon-favourite-on:active:before,
.icon-favourite-off:hover:before {
    content: "\e907";
    color: #dda500;
    text-shadow: 0 0 10px #dda500, 0 0 40px #dda500, 0 0 60px #dda500;
}

.icon-favourite-on.hovered {
    text-shadow: 0 0 10px #dda500, 0 0 40px #dda500, 0 0 60px #dda500;
    filter: brightness(1.5);
}

.icon-favourite-off:active:before,
.icon-favourite-on:active:before {
    color: #fff;
}

.favorite-link:hover .icon-favourite-on {
    color: #dda500;
    text-shadow: 0 0 10px #dda500, 0 0 40px #dda500, 0 0 60px #dda500;
}


/* this is our markdown */
.emd-drugs-terms1 p,
.drug_posology_container p {
    color: #000000 !important;
    font-family: 'open_sansregular' !important;
    font-size: 14.5px !important;
    line-height: 1.4rem !important;
}



.emd-drugs-full-descriptions h3 button,
.emd-drugs-full-descriptions .h3 button {
    padding: 1.25rem .75rem;
}

.notepad {
    background: inherit;
}

/* Tables */
.emd-drugs-full-descriptions table tr td {
    font-size: 13.5px;
    font-family: 'open_sansregular' !important;
    color: #000000;
    padding: 0.4rem;
    border: 0.1rem solid #ACACAC;
    text-align: left;
    vertical-align: top;
}

.accordion-body table tr td {
    font-size: 13.5px;
    font-family: 'open_sansregular' !important;
    color: #000000;
    padding: 0.4rem;
    border: 0.1rem solid #ACACAC;
    text-align: left;
    vertical-align: top;
}

.breadcrumb-item.active {
    font-size: 13.008px !important;
}

/* switch */

.form-switch .form-check-input {
    --bs-form-switch-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='-4 -4 8 8'%3e%3ccircle r='3' fill='%23fff'/%3e%3c/svg%3e");
    width: 2em;
    margin-left: -2.5em;
    background-image: var(--bs-form-switch-bg);
    background-position: left center;
    border-radius: 2em;
    -webkit-transition: background-position .15sease-in-out;
    transition: background-position .15sease-in-out;
}

.form-switch .form-check-input {
    border-color: #646363 !important;
    background-color: #606060 !important;

}

/* search bar */
#search-input {
    padding: 0.65rem 1rem;
}

.main-search-forms button span {
    font-size: 1.4rem;
    color: #fff;
}

.main-search-forms button {
    padding-top: 5px;
    padding-left: -5px;
}

/* notepad button */
.btn-secondary-f {
    margin-top: 20px !important;
    display: block;
    border-radius: 5px;
    border: 1px solid #1d315f;
    color: #1d315f;
    background: #fff;
    margin: 0 0 0 auto;
}

.btn-secondary-f:hover {
    background-color: #1d315f;
    ;
    color: #E3F7FF;
    transition: all 0.3s ease;
    border: 1px solid #1d315f;
}

.text-area-1 {
    outline: none;
    resize: none;
    padding: 5px;
    border: 1px transparent;
    box-shadow: 0 0 5px rgba(0, 0, 0, 0.5) !important;
    overflow-y: hidden;
}

.text-area-2 {
    display: none;
    width: 100%;
    resize: none;
    overflow: hidden;
    border: 1px transparent;
    outline: none;
    padding: 1;
    box-shadow: 0 0 5px rgba(0, 0, 0, 0.5) !important;

}

/* Notepad */
.notepad-style {
    background-color: #E3F7FF;
    border-radius: 10px;
    border: none;
    border-bottom: 1px solid transparent;
    transition: all 0.3s ease;
    font-family: 'open_sanssemibold';
    --bs-accordion-border-color: #E3F7FF
}

.notepad-style-1 {
    background-color: #E3F7FF;
    border-radius: 10px;
    border: none;
    box-shadow: 0 0 5px rgba(0, 0, 0, 0.3);

}

.btn-notepad {
    margin-bottom: 10px;
    font-size: 14.5px;
    text-align: left
}

.emd-drugs-full-descriptions .emd-notes::after {
    content: "";
    position: absolute;
    bottom: 0;
    right: 0;
    border-left: 0px solid rgba(0, 0, 0, 0);
    border-bottom: 0px solid #fff8e2;
    -webkit-transform: rotate(45deg);
    transform: rotate(0deg);
    background: none;
}

.emd-note__content {
    color: #414448;
}


.mb-41 {
    margin-bottom: 0rem !important;
}

.drugs_list {
    list-style-type: square;
    margin-top: 0pt !important;
    margin-left: 10px;
}

/* a content in sections */
.emd-drugs-accordion .emd-drugs-accordion__content a {
    color: #000;
    text-decoration: underline;
    text-decoration-thickness: 1px;
    text-decoration-color: #989898;
}

.emd-drugs-accordion .emd-drugs-accordion__content a:hover,
.emd-drugs-accordion .emd-drugs-accordion__content a:visited {
    color: #000;
}

/* a content in pop up references and references*/
.emd-drugs-full-descriptions .emd-drugs-accordion__content .accordion-body sup a,
#collapseReferences a {
    color: #33f;
    text-decoration: underline;
    -webkit-transition: all .3s ease;
    transition: all .3s ease;
    font-size: 11.5px;
}

.emd-drugs-full-descriptions .emd-drugs-accordion__content .accordion-body sup a:hover,
#collapseReferences a:hover {
    text-decoration: none;
}

.table_a_reference {
    color: #33f !important;
    text-decoration: none;
    -webkit-transition: all .3sease;
    transition: all .3sease;
    text-decoration-thickness: 1px !important;
    font-size: 11.5px !important;
    text-decoration-color: #33f !important;

}

.admin_table span, 
.admin_table td, 
.admin_table th {
    font-family: "open_sansregular", "latoregular", Arial, sans-serif;
    color: #000000 !important;
    line-height: 1.5rem !important;
    font-size: 11px !important;
}
.admin_table td a {
    font-family: "open_sansregular", "latoregular", Arial, sans-serif;
    line-height: 1.5rem !important;
    font-size: 11px !important;
}
.admin_table td {
    max-width: 200px; 
    word-wrap: break-word;
    white-space: normal;
    overflow-wrap: break-word;
}

.admin_table {
    width: 100%;
    border-collapse: collapse;
    margin-bottom: 1rem;
    white-space: wrap;
}

/* Create scrollable container for small screens */
@media (max-width: 991px) {
    .admin_table {
        display: block;
        overflow-x: auto;
    }

    .admin_table td, 
    .admin_table th {
        padding: 6px;
        font-size: 0.9rem;
    }
}


.admin_table th {
    background-color: #fff;
    border: 1px solid #ddd;
    padding: 8px;
    text-align: left;
    vertical-align: top;    
}

.admin_table td {
    border: 1px solid #ddd;
    padding: 8px;
    text-align: left;
    vertical-align: top;
}

.admin_table tr:nth-child(even) {
    background-color: #f2f2f2;
}

.admin_table td:active {
    color: lightblue !important; /* Apply active state color to all td */
}

.admin_table td.no-active:active {
    color: inherit !important; /* Prevent the color change on this td */
}

#admin_references_copy_button:active{
    background-color: lightblue ;
}